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產(chǎn)品概述
| 名稱 | KGN（人卵巢顆粒細(xì)胞）（STR鑒定正確） |
| 種屬 | 人 |
| 生長特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 成纖維細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:2-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | Granulosa cell tumor. Possible to produce progesterone after HCG addition. Cell growth is slow. |
| 年齡（性別） | 女性；69歲 |
| 組織來源 | 卵巢，腹膜 |
| 細(xì)胞類型 | 腫瘤細(xì)胞 |
| 腫瘤類型 | 卵巢癌細(xì)胞 |
| 生物安全等級 | BSL-1 |
| 倍增時(shí)間 | ~46 hours |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X CSF1PO 10,12 D2S1338 25 D3S1358 15,17 D5S818 13 D7S820 11 D8S1179 13,14 D13S317 9 D16S539 10,12 D18S51 12,14 D19S433 13,15.2 D21S11 30,32.2 FGA 25,26 PentaD 10,13 PentaE 12,21 TH01 9 TPOX 8,9 vWA 17 D6S1043 13,20 D12S391 19,21 D2S441 10,12 -
STR鑒定圖
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參考文獻(xiàn)
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Tetramethyl bisphenol F exposure induces human ovarian granulosa cell senescence and mouse ovarian damage by regulating ESRRB signalling (2025-02-27)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2025.117940
影響因子 ：6.2
引用產(chǎn)品： KGN 細(xì)胞
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Decreased miR-128-3p in serum exosomes from polycystic ovary syndrome induces ferroptosis in granulosa cells via the p38/JNK/SLC7A11 axis through targeting CSF1 (2025-02-18)
期刊：Cell Death Discovery
DOI：10.1038/s41420-025-02331-0
影響因子 ：6.1
引用產(chǎn)品： KGN 細(xì)胞
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Formononetin ameliorates polycystic ovary syndrome through suppressing NLRP3 inflammasome (2025-01-27)
期刊：MOLECULAR MEDICINE
DOI：10.1186/s10020-025-01092-x
影響因子 ：6.0
引用產(chǎn)品： KGN 細(xì)胞
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Treatment of Qin Gui Wan (QGW) in PCOS abnormal oocytes development via AMPK / PGC-1ɑ pathway (2025-01-31)
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影響因子 ：4.8
引用產(chǎn)品： KGN 細(xì)胞
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NEAT1 inhibits granulosa cell apoptosis and promotes cell growth and migration through the miR-130a-3p/BMP6 axis (2025-02-19)
期刊：REPRODUCTIVE BIOMEDICINE ONLINE
DOI：10.1016/j.rbmo.2025.104870
影響因子 ：3.7
引用產(chǎn)品： KGN 細(xì)胞
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BMAL1 improves assisted reproductive technology outcomes in patients with polycystic ovary syndrome by targeting BMP6 and regulating ovarian granulosa cell apoptosis (2025-01-24)
期刊：JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
DOI：10.1007/s10815-024-03377-2
影響因子 ：3.2
引用產(chǎn)品： KGN 細(xì)胞
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High-fat diet-induced L-saccharopine accumulation inhibits estradiol synthesis and damages oocyte quality by disturbing mitochondrial homeostasis (2024-10-16)
期刊：Gut Microbes
DOI：10.1080/19490976.2024.2412381
影響因子 ：12.2
引用產(chǎn)品： COV434 細(xì)胞 , KGN 細(xì)胞
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Advanced oxidation protein products attenuate the autophagy-lysosome pathway in ovarian granulosa cells by modulating the ROS-dependent mTOR-TFEB pathway (2024-02-21)
期刊：Cell Death & Disease
DOI：10.1038/s41419-024-06540-w
影響因子 ：9.0
引用產(chǎn)品： KGN 細(xì)胞 , COV434 細(xì)胞
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Perfluorooctane sulfonate (PFOS) induces apoptosis and autophagy by inhibition of PI3K/AKT/mTOR pathway in human granulosa cell line KGN (2024-01-09)
期刊：ENVIRONMENTAL POLLUTION
DOI：10.1016/j.envpol.2024.123333
影響因子 ：8.9
引用產(chǎn)品： KGN 細(xì)胞 , DMEM/F12 培養(yǎng)基 , 特級胎牛血清
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Berberine alleviates inflammation in polycystic ovary syndrome by inhibiting hyaluronan synthase 2 expression (2024-02-15)
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2024.155456
影響因子 ：7.9
引用產(chǎn)品： KGN 細(xì)胞
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The mechanism of curcumin to protect mouse ovaries from oxidative damage by regulating AMPK/mTOR mediated autophagy (2024-02-24)
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2024.155468
影響因子 ：7.9
引用產(chǎn)品： KGN 細(xì)胞
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Pyrroloquinoline quinone promotes human mesenchymal stem cell-derived mitochondria to improve premature ovarian insufficiency in mice through the SIRT1/ATM/p53 pathway (2024-04-05)
期刊：Stem Cell Research & Therapy
DOI：10.1186/s13287-024-03705-4
影響因子 ：7.5
引用產(chǎn)品： KGN 細(xì)胞
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METTL3 deficiency leads to ovarian insufficiency due to IL-1β overexpression in theca cells (2024-05-31)
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2024.05.048
影響因子 ：7.4
引用產(chǎn)品： KGN 細(xì)胞
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Human umbilical cord mesenchymal stem cells alleviate chemotherapy-induced premature ovarian insufficiency mouse model by suppressing ferritinophagy-mediated ferroptosis in granulosa cells (2024-04-25)
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2024.04.229
影響因子 ：7.4
引用產(chǎn)品： KGN 細(xì)胞
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TRIM28-Mediated Excessive Oxidative Stress Induces Cellular Senescence in Granulosa Cells and Contributes to Premature Ovarian Insufficiency In Vitro and In Vivo (2024-03-01)
期刊：Antioxidants
影響因子 ：7.0
引用產(chǎn)品： KGN 細(xì)胞
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Exposure to bisphenol A affects transcriptome-wide N6-methyladenine methylation in ovarian granulosa cells (2024-02-13)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2024.116071
影響因子 ：6.8
引用產(chǎn)品： KGN 細(xì)胞
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Proteomic analysis reveals that cigarette smoke exposure diminishes ovarian reserve in mice by disrupting the CREB1-mediated ovarian granulosa cell proliferation-apoptosis balance (2024-01-19)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2024.115989
影響因子 ：6.8
引用產(chǎn)品： KGN 細(xì)胞 , DMEM/F12 培養(yǎng)基 , 特級胎牛血清 , 青霉素-鏈霉素溶液 (雙抗)，100×
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A novel perspective on di-hexyl phthalate (2-ethylhexyl)-induced reproductive toxicity in females: Lipopolysaccharide synergizes with mono-2-ethylhexyl ester to cause inflammatory apoptosis rather than autophagy in ovarian granulosa cells (2024-04-13)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2024.116319
影響因子 ：6.8
引用產(chǎn)品： KGN 細(xì)胞
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Synthesis of Zinc Oxide-Doped Carbon Dots for Treatment of Triple-Negative Breast Cancer (2024-12-27)
期刊：International Journal of Nanomedicine
影響因子 ：6.6
引用產(chǎn)品： KGN 細(xì)胞 , MCF 10A 細(xì)胞 , KGN細(xì)胞專用培養(yǎng)基 , MCF 10A細(xì)胞專用培養(yǎng)基
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MiR-204 regulates autophagy and cell viability by targeting BDNF and inhibiting the NTRK2-dependent PI3K/Akt/mTOR pathway in a human granulosa cell line exposed to bisphenol A (2024-11-09)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2024.117304
影響因子 ：6.2
引用產(chǎn)品： KGN 細(xì)胞
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USP14 inhibition promotes DNA damage repair and represses ovarian granulosa cell senescence in premature ovarian insufficiency (2024-09-11)
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-05636-3
影響因子 ：6.1
引用產(chǎn)品： 293T [HEK-293T] 細(xì)胞 , KGN 細(xì)胞
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Indole-3-carbinol ameliorates ovarian damage in female old mice through Nrf2/HO-1 pathway activation (2024-04-04)
期刊：BIOCHEMICAL PHARMACOLOGY
影響因子 ：5.3
引用產(chǎn)品： KGN 細(xì)胞
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miR-21-loaded bone marrow mesenchymal stem cell-derived exosomes inhibit pyroptosis by targeting MALT1 to repair chemotherapy-induced premature ovarian insufficiency (2024-12-20)
期刊：CELL BIOLOGY AND TOXICOLOGY
DOI：10.1007/s10565-024-09946-6
影響因子 ：5.3
引用產(chǎn)品： 小鼠骨髓間充質(zhì)干細(xì)胞 , KGN 細(xì)胞
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Toxicity mechanism of acrolein on energy metabolism disorder and apoptosis in human ovarian granulosa cells (2024-06-10)
期刊：TOXICOLOGY
影響因子 ：4.8
引用產(chǎn)品： KGN 細(xì)胞
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Chinese medicine compound prescription HeQi San ameliorates chronic inflammatory states and modulates gut flora in dehydroepiandrosterone-induced polycystic ovary syndrome mouse model (2024-06-22)
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2024.112491
影響因子 ：4.8
引用產(chǎn)品： KGN 細(xì)胞 , THP-1 細(xì)胞
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SFRP4 contributes to insulin resistance-induced polycystic ovary syndrome by triggering ovarian granulosa cell hyperandrogenism and apoptosis through the nuclear β-catenin/IL-6 signaling axis (2024-08-17)
期刊：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
DOI：10.1016/j.bbamcr.2024.119822
影響因子 ：4.6
引用產(chǎn)品： KGN 細(xì)胞
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Human Amniotic Epithelial Stem Cells Alleviate Autoimmune Premature Ovarian Insufficiency in Mice by Targeting Granulosa Cells via AKT/ERK Pathways (2024-06-04)
期刊：Stem Cell Reviews and Reports
DOI：10.1007/s12015-024-10745-z
影響因子 ：4.5
引用產(chǎn)品： KGN 細(xì)胞 , 青霉素-鏈霉素溶液（雙抗），100×
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Endometrial stem cells alleviate cisplatin-induced ferroptosis of granulosa cells by regulating Nrf2 expression (2024-04-11)
期刊：Reproductive Biology and Endocrinology
DOI：10.1186/s12958-024-01208-8
影響因子 ：4.4
引用產(chǎn)品： KGN 細(xì)胞
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Epigenomic Landscape of Human Cumulus Cells in Premature Ovarian Insufficiency Using Single-Base Resolution Methylome and Hydroxymethylome (2024-12-20)
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影響因子 ：4.3
引用產(chǎn)品： KGN 細(xì)胞
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PAI-1 siRNA-loaded biomimetic nanoparticles for ameliorating diminished ovarian reserve and inhibiting ovarian fibrosis (2024-08-30)
期刊：EUROPEAN JOURNAL OF PHARMACOLOGY
DOI：10.1016/j.ejphar.2024.176948
影響因子 ：4.2
引用產(chǎn)品： KGN 細(xì)胞
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Design, synthesis and biological evaluation of rhein–piperazine–furanone hybrids as potential anticancer agents (2024-02-13)
期刊：RSC Medicinal Chemistry
影響因子 ：4.1
引用產(chǎn)品： A549 [A-549] 細(xì)胞 , NCI-H460 [H460] 細(xì)胞 , PC-9 細(xì)胞 , Calu-1 細(xì)胞 , SK-BR-3 [SKBR3] 細(xì)胞 , SK-OV-3 細(xì)胞 , 786-O [786-0] 細(xì)胞 , HuH-7 細(xì)胞 , HCT 116 細(xì)胞 , Hela 細(xì)胞 , WI-38 細(xì)胞 , MCF 10A 細(xì)胞 , KGN 細(xì)胞 , 293T [HEK-293T] 細(xì)胞 , DMEM高糖 培養(yǎng)基 , MEM 培養(yǎng)基 , DMEM/F12 培養(yǎng)基 , McCoy's 5A 培養(yǎng)基 , RPMI-1640 培養(yǎng)基 , 0.25%胰蛋白酶溶液 (含EDTA，溶于PBS)
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Endometrial stem cell-derived exosomes repair cisplatin-induced premature ovarian failure via Hippo signaling pathway (2024-05-20)
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e31639
影響因子 ：4.0
引用產(chǎn)品： KGN 細(xì)胞
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miR-21-loaded BMSC-derived Exosomes repair ovarian function of autoimmune premature ovarian insufficiency by targeting MSX1 (2024-01-09)
期刊：REPRODUCTIVE BIOMEDICINE ONLINE
DOI：10.1016/j.rbmo.2024.103815
影響因子 ：4.0
引用產(chǎn)品： 小鼠骨髓間充質(zhì)干細(xì)胞 , KGN 細(xì)胞
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FTO attenuates the cytotoxicity of cisplatin in KGN granulosa cell-like tumour cells by regulating the Hippo/YAP1 signalling pathway (2024-03-15)
期刊：Journal of Ovarian Research
DOI：10.1186/s13048-024-01385-5
影響因子 ：4.0
引用產(chǎn)品： KGN 細(xì)胞
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Cyclophosphamide induces ovarian granulosa cell ferroptosis via a mechanism associated with HO-1 and ROS-mediated mitochondrial dysfunction (2024-05-18)
期刊：Journal of Ovarian Research
DOI：10.1186/s13048-024-01434-z
影響因子 ：4.0
引用產(chǎn)品： KGN 細(xì)胞 , COV434 細(xì)胞
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Exosomes derived from bone marrow mesenchymal stem cells attenuate NLRP3 related pyroptosis in autoimmune premature ovarian insufficiency via NF-κB pathway (2024-01-09)
期刊：REPRODUCTIVE BIOMEDICINE ONLINE
DOI：10.1016/j.rbmo.2024.103814
影響因子 ：4.0
引用產(chǎn)品： 小鼠骨髓間充質(zhì)干細(xì)胞 , KGN 細(xì)胞
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Human mesenchymal stem cells derived exosomes improve ovarian function in chemotherapy-induced premature ovarian insufficiency mice by inhibiting ferroptosis through Nrf2/GPX4 pathway (2024-04-15)
期刊：Journal of Ovarian Research
DOI：10.1186/s13048-024-01403-6
影響因子 ：4.0
引用產(chǎn)品： KGN 細(xì)胞
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Transcription factor YY1 adversely governs ovarian granulosa cell growth in PCOS by transcription activation-mediated CDKN1C upregulation (2024-09-25)
期刊：FUNCTIONAL & INTEGRATIVE GENOMICS
DOI：10.1007/s10142-024-01448-2
影響因子 ：3.9
引用產(chǎn)品： KGN 細(xì)胞 , KGN細(xì)胞專用培養(yǎng)基 , 293T [HEK-293T] 細(xì)胞
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ATF3 mediates PM2.5-induced apoptosis and inflammation in ovarian granulosa cells (2024-11-05)
期刊：Journal of Ovarian Research
DOI：10.1186/s13048-024-01539-5
影響因子 ：3.8
引用產(chǎn)品： KGN 細(xì)胞 , DMEM/F12完全培養(yǎng)基（含HEPES、10% FBS）
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Protective effect of afamin protein against oxidative stress related injury in human ovarian granulosa cells (2024-09-28)
期刊：Journal of Ovarian Research
DOI：10.1186/s13048-024-01511-3
影響因子 ：3.8
引用產(chǎn)品： KGN 細(xì)胞
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Follicular fluid-derived extracellular vesicles miR-34a-5p regulates granulosa cell glycolysis in polycystic ovary syndrome by targeting LDHA (2024-11-13)
期刊：Journal of Ovarian Research
DOI：10.1186/s13048-024-01542-w
影響因子 ：3.8
引用產(chǎn)品： KGN 細(xì)胞
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A quinoline-2-thione derivative as a novel chemotherapy drug candidate displays anti-tumor activity in vitro and in vivo (2024-10-13)
期刊：BMC CANCER
DOI：10.1186/s12885-024-13042-7
影響因子 ：3.4
引用產(chǎn)品： KGN 細(xì)胞
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Tenascin C activates the toll?like receptor 4/NF?κB signaling pathway to promote the development of polycystic ovary syndrome (2024-04-25)
期刊：Molecular Medicine Reports
影響因子 ：3.4
引用產(chǎn)品： DMEM/F12 培養(yǎng)基 , KGN 細(xì)胞
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Excessive fluoride induces ovarian function impairment by regulating levels of ferroptosis in fluorosis women and ovarian granulosa cells (2024-02-09)
期刊：REPRODUCTIVE TOXICOLOGY
DOI：10.1016/j.reprotox.2024.108556
影響因子 ：3.3
引用產(chǎn)品： KGN 細(xì)胞
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Potential mechanism prediction of indole-3-propionic acid against diminished ovarian reserve via network pharmacology, molecular docking and experimental verification (2024-08-27)
期刊：BMC Complementary Medicine and Therapies
DOI：10.1186/s12906-024-04611-1
影響因子 ：3.3
引用產(chǎn)品： KGN 細(xì)胞
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The melatonin-FTO-ATF4 signaling pathway protects granulosa cells from cisplatin-induced chemotherapeutic toxicity by suppressing ferroptosis (2024-10-10)
期刊：JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
DOI：10.1007/s10815-024-03276-6
影響因子 ：3.2
引用產(chǎn)品： KGN 細(xì)胞
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SOX4 regulates proliferation and apoptosis of human ovarian granulosa-like tumor cell line KGN through the Hippo pathway (2024-02-27)
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2024.149738
影響因子 ：3.1
引用產(chǎn)品： KGN 細(xì)胞
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Nuciferine protects hyperandrogen-injured ovarian granulosa cells by inhibiting ferroptosis via SOX2-mediated activation of the SLC7A11/GPX4 axis (2024-09-16)
期刊：JOURNAL OF APPLIED TOXICOLOGY
DOI：10.1002/jat.4697
影響因子 ：2.7
引用產(chǎn)品： KGN 細(xì)胞
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NOX4 deficiency improves the impaired viability, inhibited the apoptosis and suppressed autophagy of DHEA-treated ovarian granulosa cells through inhibiting endoplasmic reticulum stress via inactivating PERK/ATF4 pathway (2024-11-28)
期刊：TISSUE & CELL
DOI：10.1016/j.tice.2024.102640
影響因子 ：2.7
引用產(chǎn)品： KGN 細(xì)胞
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Menstrual Blood-Derived Endometrial Stem Cells Ameliorate Ovarian Senescence by Relieving Oxidative Stress-Induced Inflammation (2024-11-05)
期刊：Reproductive Sciences
DOI：10.1007/s43032-024-01739-w
影響因子 ：2.6
引用產(chǎn)品： KGN 細(xì)胞
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Naringenin mitigates cadmium-induced cell death, oxidative stress, mitochondrial dysfunction, and inflammation in KGN cells by regulating the expression of sirtuin-1 (2024-04-22)
期刊：DRUG AND CHEMICAL TOXICOLOGY
DOI：10.1080/01480545.2023.2288798
影響因子 ：2.6
引用產(chǎn)品： KGN 細(xì)胞
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Circ_0043314 modulates proliferation and apoptosis of ovarian granulosa cells in polycystic ovarian syndrome via the microRNA-146b-3p/Apelin 13 axis (2024-07-16)
期刊：GYNECOLOGIC AND OBSTETRIC INVESTIGATION
影響因子 ：2.0
引用產(chǎn)品： 293T [HEK-293T] 細(xì)胞 , KGN 細(xì)胞
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Lycopene mitigates DHT-induced apoptosis and oxidative stress in human granulosa cell line KGN by regulating the Nrf2 pathway (2024-02-05)
期刊：Molecular & Cellular Toxicology
DOI：10.1007/s13273-023-00419-1
影響因子 ：1.7
引用產(chǎn)品： KGN 細(xì)胞
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Quercetin and tanshinone prevent mitochondria from oxidation and autophagy to inhibit KGN cell apoptosis through the SIRT1/SIRT3-FOXO3a axis (2024-02-29)
期刊：CELLULAR AND MOLECULAR BIOLOGY
影響因子 ：1.6
引用產(chǎn)品： KGN 細(xì)胞
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Metformin enhances the survival ability of ovarian granulosa cells in polycystic ovary syndrome by promoting LINC00548 to suppress androgen receptor/klotho pathway (2024-08-21)
期刊：JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
影響因子 ：1.6
引用產(chǎn)品： Annexin V-FITC/DAPI熒光雙染細(xì)胞凋亡檢測試劑盒 , 一步法TUNEL原位細(xì)胞凋亡檢測試劑盒（紅色，PriFluor 594） , 青霉素-鏈霉素溶液（雙抗），100× , DMEM/F12 培養(yǎng)基 , 特級胎牛血清 , KGN 細(xì)胞
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BCAA insufficiency leads to premature ovarian insufficiency via ceramide-induced elevation of ROS (2023-02-27)
期刊：EMBO Molecular Medicine
影響因子 ：11.1
引用產(chǎn)品： KGN 細(xì)胞
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In utero bisphenol A exposure disturbs germ cell cyst breakdown through the PI3k/Akt signaling pathway and BDNF expression (2023-05-19)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2023.115031
影響因子 ：6.8
引用產(chǎn)品： KGN 細(xì)胞
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Activation of the p62-Keap1-Nrf2 pathway protects against oxidative stress and excessive autophagy in ovarian granulosa cells to attenuate DEHP-induced ovarian impairment in mice (2023-09-28)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2023.115534
影響因子 ：6.8
引用產(chǎn)品： KGN 細(xì)胞
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LncRNA SNHG5 adversely governs follicular growth in PCOS via miR-92a-3p/CDKN1C axis (2023-11-23)
期刊：iScience
DOI：10.1016/j.isci.2023.108522
影響因子 ：5.8
引用產(chǎn)品： KGN 細(xì)胞
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FGF2 Rescued Cisplatin-Injured Granulosa Cells through the NRF2-Autophagy Pathway (2023-09-18)
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影響因子 ：5.6
引用產(chǎn)品： KGN 細(xì)胞 , DMEM/F12 培養(yǎng)基
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Adenosine receptor A2b confers ovarian cancer survival and PARP inhibitor resistance through IL-6-STAT3 signalling (2023-06-06)
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影響因子 ：5.3
引用產(chǎn)品： Hey 細(xì)胞 , KGN 細(xì)胞
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Inhibition of cisplatin-induced Acsl4-mediated ferroptosis alleviated ovarian injury (2023-12-05)
期刊：CHEMICO-BIOLOGICAL INTERACTIONS
影響因子 ：5.1
引用產(chǎn)品： KGN 細(xì)胞
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25(OH)D3 improves granulosa cell proliferation and IVF pregnancy outcomes in patients with endometriosis by increasing G2M+S phase cells (2023-12-05)
期刊：Reproductive Biology and Endocrinology
DOI：10.1186/s12958-023-01165-8
影響因子 ：4.4
引用產(chǎn)品： KGN 細(xì)胞 , KGN細(xì)胞專用培養(yǎng)基
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BMP4 participates in the pathogenesis of PCOS by regulating glucose metabolism and autophagy in granulosa cells under hyperandrogenic environment (2023-10-18)
期刊：JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
DOI：10.1016/j.jsbmb.2023.106410
影響因子 ：4.1
引用產(chǎn)品： KGN 細(xì)胞 , DMEM/F12 培養(yǎng)基
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Roles of follicle stimulating hormone and sphingosine 1-phosphate co-administered in the process in mouse ovarian vitrification and transplantation (2023-08-24)
期刊：Journal of Ovarian Research
DOI：10.1186/s13048-023-01206-1
影響因子 ：4.0
引用產(chǎn)品： KGN 細(xì)胞
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Pterostilbene ameliorates oxidative damage and ferroptosis in human ovarian granulosa cells by regulating the Nrf2/HO-1 pathway (2023-03-09)
期刊：ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
影響因子 ：3.9
引用產(chǎn)品： COV434 細(xì)胞 , KGN 細(xì)胞
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Baicalin suppress the development of polycystic ovary syndrome via regulating the miR-874-3p/FOXO3 and miR-144/FOXO1 axis (2023-06-05)
期刊：PHARMACEUTICAL BIOLOGY
DOI：10.1080/13880209.2023.2208636
影響因子 ：3.8
引用產(chǎn)品： KGN 細(xì)胞
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PDE4 inhibitor Roflumilast modulates inflammation and lipid accumulation in PCOS mice to improve ovarian function and reduce DHEA-induced granulosa cell apoptosis in vitro (2023-01-09)
期刊：DRUG DEVELOPMENT RESEARCH
影響因子 ：3.8
引用產(chǎn)品： KGN 細(xì)胞
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Whole exome sequencing reveals novel variants associated with diminished ovarian reserve in young women (2023-03-29)
期刊：Frontiers in Genetics
DOI：10.3389/fgene.2023.1154067
影響因子 ：3.7
引用產(chǎn)品： KGN 細(xì)胞
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Follicular fluid derived exosomal miR-4449 regulates cell proliferation and oxidative stress by targeting KEAP1 in human granulosa cell lines KGN and COV434 (2023-07-29)
期刊：EXPERIMENTAL CELL RESEARCH
DOI：10.1016/j.yexcr.2023.113735
影響因子 ：3.7
引用產(chǎn)品： KGN 細(xì)胞 , COV434 細(xì)胞 , 293T [HEK-293T] 細(xì)胞
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Identification of nonfunctional PABPC1L causing oocyte maturation abnormalities and early embryonic arrest in female primary infertility (2023-09-18)
期刊：CLINICAL GENETICS
影響因子 ：3.5
引用產(chǎn)品： KGN 細(xì)胞
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Kisspeptin regulates the proliferation and apoptosis of ovary granulosa cells in polycystic ovary syndrome by modulating the PI3K/AKT/ERK signalling pathway (2023-01-11)
期刊：BMC Womens Health
DOI：10.1186/s12905-022-02154-6
影響因子 ：2.5
引用產(chǎn)品： KGN 細(xì)胞
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CDKN2B-AS1 is overexpressed in polycystic ovary syndrome and sponges miR-181a to promote granulosa cell proliferation (2023-10-06)
期刊：ANTI-CANCER DRUGS
DOI：10.1097/CAD.0000000000001405
影響因子 ：2.3
引用產(chǎn)品： 人卵巢顆粒細(xì)胞
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N6-methyladenosine demethylase FTO related to hyperandrogenism in PCOS via AKT pathway (2023-11-06)
期刊：GYNECOLOGICAL ENDOCRINOLOGY
DOI：10.1080/09513590.2023.2276167
影響因子 ：2.0
引用產(chǎn)品： KGN 細(xì)胞
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Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failure (2023-07-27)
期刊：EUROPEAN JOURNAL OF HISTOCHEMISTRY
影響因子 ：2.0
引用產(chǎn)品： 人臍帶間充質(zhì)干細(xì)胞 , KGN 細(xì)胞
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KLF4 overexpression facilitates proliferation and represses apoptosis of granulosa cells in polycystic ovary syndrome (2023-06-27)
期刊：Molecular & Cellular Toxicology
DOI：10.1007/s13273-023-00354-1
影響因子 ：1.7
引用產(chǎn)品： KGN 細(xì)胞
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Glioma-Associated Oncogene Family Zinc Finger 2 (GLI2) Activates Wnt Signaling through Transcriptional Inhibition of Neuronal Precursor Cell-Expressed Developmentally Downregulated 4 (NEDD4L) to Promote Androgen-Induced Granulosa Cell Damage (2023-01-01)
期刊：ANNALS OF CLINICAL AND LABORATORY SCIENCE
DOI：PMID:36889770
影響因子 ：0.8
引用產(chǎn)品： KGN 細(xì)胞
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The Effects of Abscisic Acid Administration in PCOS Rat Model and H2O2-Induced Human Granulosa Cell Damage: A Preliminary Investigation (2023-06-12)
期刊：Clinical and Experimental Obstetrics & Gynecology
影響因子 ：0.2
引用產(chǎn)品： KGN 細(xì)胞
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RNA binding protein IGF2BP1 meditates oxidative stress-induced granulosa cell dysfunction by regulating MDM2 mRNA stability in an m6A-dependent manner (2022-09-24)
期刊：Redox Biology
DOI：10.1016/j.redox.2022.102492
影響因子 ：10.8
引用產(chǎn)品： KGN 細(xì)胞 , 293T [HEK-293T] 細(xì)胞
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The E3 Ubiquitin Ligase SYVN1 Plays an Antiapoptotic Role in Polycystic Ovary Syndrome by Regulating Mitochondrial Fission. (2022-09-19)
期刊：Oxidative Medicine and Cellular Longevity
影響因子 ：7.3
引用產(chǎn)品： KGN 細(xì)胞
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Single-nucleus RNA Sequencing reveals the mechanism of cigarette smoke exposure on diminished ovarian reserve in mice (2022-09-16)
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2022.114093
影響因子 ：7.1
引用產(chǎn)品： KGN 細(xì)胞
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NUF2 overexpression contributes to epithelial ovarian cancer progression via ERBB3-mediated PI3K-AKT and MAPK signaling axes. (2022-12-21)
期刊：Frontiers in Oncology
影響因子 ：5.7
引用產(chǎn)品： KGN 細(xì)胞
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GIMAP7 induces oxidative stress and apoptosis of ovarian granulosa cells in polycystic ovary syndrome by inhibiting sonic hedgehog signalling pathway (2022-12-30)
期刊：Journal of Ovarian Research
DOI：10.1186/s13048-022-01092-z
影響因子 ：5.5
引用產(chǎn)品： KGN 細(xì)胞
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Kurarinone attenuates hydrogen peroxide-induced oxidative stress and apoptosis through activating the PI3K/Akt signaling by upregulating IGF1 expression in human ovarian granulosa cells (2022-09-17)
期刊：ENVIRONMENTAL TOXICOLOGY
影響因子 ：4.1
引用產(chǎn)品： KGN 細(xì)胞
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The cytokine profiles in follicular fluid and reproductive outcomes in women with endometriosis (2022-10-17)
期刊：AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
影響因子 ：3.8
引用產(chǎn)品： KGN 細(xì)胞
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Melatonin suppresses serum starvation-induced autophagy of ovarian granulosa cells in premature ovarian insufficiency (2022-11-24)
期刊：BMC Womens Health
DOI：10.1186/s12905-022-02056-7
影響因子 ：2.7
引用產(chǎn)品： KGN 細(xì)胞
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CircRNA circ_0043533 facilitates cell growth in polycystic ovary syndrome by targeting miR-1179 (2022-03-25)
期刊：Reproductive Biology
DOI：10.1016/j.repbio.2022.100637
影響因子 ：2.1
引用產(chǎn)品： KGN 細(xì)胞 , COV434 細(xì)胞
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SMAD4-induced knockdown of the antisense long noncoding RNA BRE-AS contributes to granulosa cell apoptosis (2021-05-14)
期刊：Molecular Therapy-Nucleic Acids
DOI：10.1016/j.omtn.2021.05.006
影響因子 ：8.8
引用產(chǎn)品： KGN 細(xì)胞
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The Release of Peripheral Immune Inflammatory Cytokines Promote an Inflammatory Cascade in PCOS Patients via Altering the Follicular Microenvironment (2021-05-17)
期刊：Frontiers in Immunology
影響因子 ：7.3
引用產(chǎn)品： KGN 細(xì)胞
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Circadian Clock Genes REV-ERBs Inhibits Granulosa Cells Apoptosis by Regulating Mitochondrial Biogenesis and Autophagy in Polycystic Ovary Syndrome (2021-08-05)
期刊：Frontiers in Cell and Developmental Biology
影響因子 ：5.5
引用產(chǎn)品： KGN 細(xì)胞
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MiR-1224-5p attenuates polycystic ovary syndrome through inhibiting NOD-like receptor protein 3 inflammasome activation via targeting Forkhead box O 1 (2021-10-21)
期刊：Bioengineered
DOI：10.1080/21655979.2021.1987125
影響因子 ：4.9
引用產(chǎn)品： KGN 細(xì)胞 , DMEM/F12 培養(yǎng)基
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DNA Methylation Profiles of Ovarian Granular Cells from Fluorosis Female Patients Suffering Reproductive Dysfunctions (2021-10-22)
期刊：Biological Trace Element Research
DOI：10.1007/s12011-021-02954-1
影響因子 ：4.1
引用產(chǎn)品： KGN 細(xì)胞
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miR-378d is Involved in the Regulation of Apoptosis and Autophagy of and E 2 Secretion from Cultured Ovarian Granular Cells Treated by Sodium Fluoride (2021-01-06)
期刊：BIOLOGICAL TRACE ELEMENT RESEARCH
DOI：10.1007/s12011-020-02524-x
影響因子 ：3.9
引用產(chǎn)品： KGN 細(xì)胞
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